XTMS: Pathway Search in an eXTended Metabolic Space: About

The XTMS web server provides access to the set of available pathways that can be imported into E. coli based on an Extended Metabolic Space, i.e. on the set of potential in vivo biochemical transformations as modeled by extended connectivity fingerprints at the atom neighborhood diameters of d = 14, 12, and 10 (Carbonell et al., 2011).

Most promising routes are described in terms of metabolite exchange, maximum allowable pathway yield, toxicity, and enzyme efficiency.

Parts contributed by: P. Carbonell, P. Parutto, J. Herisson, S. Pandit, J.L. Faulon.

How to cite:
  • Carbonell, P., Parutto, P., Herisson, J., Pandit, S., Faulon, J.L. XTMS: Pathway design in an eXTended Metabolic Space. Nucleic Acids Research, 2014.